Our annual cruise guide provides an in-depth look at the amazing U.S. ports and destinations we visit, our modern fleet of riverboats, excursions and adventures on shore, our onboard amenities and …

Trace the route of Lewis and Clark aboard modern riverboats. Cruise dramatic gorges, waterfalls, Mount St. Helens, plus sample Pacific Northwest cuisine.

Pricing for American Cruise Lines' Mississippi River itineraries varies based on the length of the cruise and any optional excursions you choose to add. The cost of Mississippi River cruises can vary widely …

Cruise Southeastern rivers and coastlines exploring historic coastal towns, lush waterways, charming ports, all-inclusive service, and regional cuisine.

Enjoy the charm of Nantucket, Martha's Vineyard, and Block Island on our New England Islands Cruise. Take in rich maritime history on this journey.

Search over 50 U.S. cruise itineraries by region, date, or ship class. View highlights, local excursions, rates, and availability to find your perfect cruise.

Learn about American Cruise Lines, an all-American cruise company offering small ship and river cruises across 35 states and 50+ itineraries.

Find limited-time savings on small-ship U.S. river and coastal cruises. Packages include airfare options, upgrades, and extra flexibility for your travel plans.

Enjoy US Riverboat Cruises along the Southeast, New England, Alaska, Pacific Northwest & Mississippi River with a variety of cruise ships & themes.

Charming New England Cruises The islands and harbors of New England are among the most desired summer vacation retreats. From the quaint island villages of Nantucket and Martha's Vineyard to the …